Brand | Yusi Pharma | ||
---|---|---|---|
IUPAC Name | Doxorubicin-polyethylene glycol-hydrazone bond-folic acid | ||
Abbreviations | DOX-hyd-PEG-FA FA-PEG-hyd-DOX | ||
Parameters | |||
CAS | Compound CID | YD-PEG-4971 | |
MF | MW |
Serial Number | Norm | Catalogue Price | Stocks |
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Note: In the case of dangerous goods, low-temperature transport products, IATA products and other products that require special transport, freight and other related charges may be added according to the actual situation.
I. [Product Description]
DOX-hyd-PEG-FA is a functionalized polyethylene glycol derivative that connects doxorubicin and folic acid through a hydrazone bond. As a high-performance organic intermediate, it is suitable for constructing targeted nano drug delivery systems. The pH-sensitive hydrazone bond and the FA targeting group in its structure endow it with the precise controlled-release characteristics as a pharmaceutical intermediate. Meanwhile, the PEG segment provides excellent water solubility and biocompatibility, and shows high-efficiency stability in catalytic coupling reactions.
II. [Product Details]
【Appearance】 Depending on different molecular weights, it appears as a white/off-white solid or a viscous liquid.
【Stability】 Store under refrigeration and avoid repeated freezing and thawing.
【Solvent】 Conventional organic solvents such as chloroform, dichloromethane, and DMSO.
【Molecular Weight】 (PEG): 2000, 3400, 5000. Other molecular weights can be customized.
【Storage Conditions】 Store at a low temperature below 4°C in a sealed and dry environment.
▪ Note: ▶ To ensure product stability, please note that the package should be opened for use only after constant-temperature drying!
III. [Application Areas]
1. Construction of targeted nano drug carriers (Journal of Controlled Release, 2023)
2. Development of pH-responsive intelligent materials (ACS Applied Materials & Interfaces, 2022)
3. Functional linking arms in bioconjugation reactions (Bioconjugate Chemistry, 2021)
4. Controllable release systems responsive to the tumor microenvironment (Advanced Drug Delivery Reviews, 2020)
5. Functional modification of folate receptor overexpression systems (Nanoscale, 2019)
Remarks: The products sold by our company are only for scientific research and cannot be used for human experiments or human treatment.
Chongqing Yusi Pharmaceutical Technology Co., Ltd. operates based on an integrated business model of independent R & D-production-sales, providing professional scientific research reagents for university scientific research experiments. Compared with similar products on the market, our company's products have obvious price advantages. In addition, we also provide professional product customization services.
If you need other products, please contact us:
Contact Information:
Landline: 023-62795528
Customer Service Hotline: 18896157519 丨 QQ: 3354316092
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Recommendation of Similar Products:
1. FA-PEG-NHS (Folic acid-polyethylene glycol-active ester)
2. MAL-PEG-Hydrazide (Maleimide-PEG-hydrazide)
3. PLGA-PEG-FA (Poly(lactic-co-glycolic acid)-PEG-folic acid)
4. DOX-PEG-SH (Doxorubicin-PEG-mercapto)
5. PEG-Cy5-Hydrazone (Cy5-labeled hydrazone-bond PEG)
6. FA-PEG-COOH (Folic acid-polyethylene glycol-carboxylic acid)
7. mPEG-HZ-TOS (Methoxy PEG-hydrazone bond-p-toluenesulfonate)
8. PLGA-PEG-MAL (PLGA-PEG-maleimide)
9. PEG-SS-COOH (Disulfide bond-PEG-carboxylic acid)
10. HA-PEG-DOX (Hyaluronic acid-PEG-doxorubicin)
11. PEG-PCL-Hydrazone (PEG-polycaprolactone-hydrazone bond)
12. FA-PEG-SH (Folic acid-PEG-mercapto)
13. PEG-GFLG-DOX (Enzyme-responsive peptide-PEG-doxorubicin)
14. PLGA-PEG-NH2 (PLGA-PEG-amino)
15. PEG-PAsp-Hydrazone (PEG-polyaspartic acid-hydrazone bond)
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