I. [Product Description]
DOX-PEG-Hyd-PMLA is a composite organic intermediate constructed based on a poly(malic acid) (PMLA) carrier. It forms a modular structure with pH-responsive properties by connecting doxorubicin derivatives and PEG of different molecular weights through a hydrazone bond. This compound can be used as a pharmaceutical intermediate to construct intelligent delivery systems. Its PEG segment can be customized to adjust the hydrophilic-lipophilic balance, and the poly(malic acid) main chain provides high loading capacity, which is suitable for directional modification in catalytic reaction systems.

II. [Product Details]
【Appearance】 Off-white to pale yellow solid, semi-transparent viscous jelly when the molecular weight ≥ 5000
【Stability】 Store at -20°C for long-term. Use within 48 hours after dissolution.
【Solvents】 Anhydrous DMSO, THF/water mixture (v:v = 7:3), dimethylacetamide
【Molecular Weight】 (PEG): 2000 ± 50, 3400 ± 80, 5000 ± 100 (customizable in the range of 1000-10000)
【Storage Conditions】 Packed in a nitrogen-filled aluminum foil bag, store at -20°C in the dark. The shelf life is 18 months.
▪ Precautions: ▶ After thawing, equilibrate in a vacuum drying oven at 25°C for 2 hours before opening!

III. [Application Areas]
1. Construction of a controllable self-assembly system for functionalized polymer materials (ACS Macro Lett. 2022)
2. Surface modification of biocompatible nanoreactors (Adv. Mater. Interfaces 2023)
3. Chemical coupling of stimulus-responsive molecular probes (J. Colloid Interface Sci. 2021)
4. Interface modification of organic-inorganic hybrid materials (Chem. Eng. J. 2023)
5. Multifunctional coating technology for catalytic carriers (Catal. Sci. Technol. 2022)

Note: The products sold by our company are only for scientific research and cannot be used in human experiments or human treatment.

Chongqing Yusi Pharmaceutical Technology Co., Ltd. is based on an integrated R & D-production-sales business model, providing professional scientific research reagents for university scientific research experiments. Compared with similar products on the market, our company's products have obvious price advantages. In addition, we also provide professional product customization services.

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Contact Information:
Landline: 023-62795528
Customer Service Hotline: 19112925095 丨 QQ: 3012135199
                                           18896157519 丨 QQ: 3354316092

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