I. [Product Introduction]
SPDP-PEG-Mal, 3-(2-pyridyldithio)propionic acid N-hydroxysuccinimide ester-polyethylene glycol-maleimide, is a multifunctional organic intermediate. It combines high-efficiency thiol reactivity with biocompatibility and is widely used in protein conjugation, polymer material modification, and catalytic reaction systems. The 2-pyridyldithio group in its structure can serve as a reversible crosslinking agent, while the maleimide group enables precise thiol coupling. The customizable PEG chain enhances water solubility and stability. It is a key reagent for the development of pharmaceutical intermediates and the assembly of complex molecules.

II. [Product Details]
【Appearance】 Depending on different molecular weights, it appears as a white/off-white solid or a viscous liquid.
【Stability】 Store it in a refrigerator and avoid repeated freezing and thawing.
【Solvent】 Conventional organic solvents such as chloroform, dichloromethane, and DMSO.
【Molecular Weight】 (PEG): 2000, 3400, 5000. Other molecular weights can be customized.
【Storage Conditions】 Store it in a sealed and dry condition at a low temperature below 4°C.
▪ Notes: ▶ To ensure product stability, please open the package for use only after constant-temperature drying!

III. [Application Fields]
1. Bioconjugation of macromolecules: Directional crosslinking of proteins/antibodies through the disulfide bond exchange of the SPDP group.
2. Surface modification of nanomaterials: Specific binding of the maleimide group to thiolated nanoparticles.
3. Construction of polymer drug carriers: Utilize the PEG chain to enhance the stability and long-circulation properties of the drug delivery system.
4. Enzyme immobilization technology: High-efficiency covalent coupling of the NHS ester group with amino substrates.
5. Development of diagnostic reagents: Design responsive probes based on the reversible connection mechanism of pyridyldithio.

Remarks: The products sold by our company are only for scientific research and cannot be used in human experiments or human treatment.

Chongqing Yusi Pharmaceutical Technology Co., Ltd. operates under an integrated business model of self-research, production, and sales. It provides professional scientific research reagents for university scientific research experiments. Compared with similar products on the market, our company's products have obvious price advantages. In addition, we also offer professional product customization services.

If you need other products, please contact us:
Contact Information:
Landline: 023-62795528
Customer Service Hotline: 19112925095 丨 QQ: 3012135199
                                           18896157519 丨 QQ: 3354316092

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