Cyanine7-NH2 has diverse applications in life sciences and medicine. The following are specific applications and corresponding examples of Cyanine7-NH2 in different applications:

 

1. Biofluorescence imaging: The near-infrared fluorescent nature of Cyanine7-NH2 makes it an ideal tool for fluorescence imaging in organisms. For example, Cyanine7-NH2 is labeled on specific proteins or antibodies for NIR fluorescence imaging to study the distribution and localization of proteins in organisms.

 

2. Cell tracing: Cyanine7-NH2 can be used to track and localize the migration and localization of specific cells or cell populations in vivo. For example, Cyanine7-NH2 is labeled on a cellular tracer dye for use in near-infrared fluorescence imaging to track the metastasis and localization of tumor cells.

 

3. Molecular probes: Cyanine7-NH2 can be labeled on molecular probes for the detection and quantification of the presence and concentration changes of specific biomolecules. For example, Cyanine7-NH2 is labeled on DNA or RNA probes for use in near-infrared fluorescence imaging to detect nucleic acid content and localization within cells.

 

4. Fluorescent labeling: Cyanine7-NH2 can be used to fluorescently label and analyze compounds or biomolecules. For example, Cyanine7-NH2 is labeled on drug molecules for near-infrared fluorescence imaging of drug distribution and metabolism.

 

5. Neuroscience: Cyanine7-NH2 can be used for near-infrared fluorescence imaging in neuroscience research. For example, labeling Cyanine7-NH2 on neuron-specific proteins is used to study neuronal connectivity and activity.

 

In conclusion, Cyanine7-NH2 has a wide range of applications in life sciences and medicine, including biofluorescence imaging, cell tracing, molecular probing, fluorescent labeling, and neuroscience research. By labeling Cyanine7-NH2 on specific molecules or probes, high-resolution observation and quantitative analysis of specific structures and molecules in organisms can be achieved. Due to the near-infrared fluorescence property of Cyanine7-NH2, it can be used for biomedical imaging under the condition of lower background signal to improve the sensitivity and resolution of imaging.